Dissolution Tester

A Dissolution Tester is a critical analytical instrument designed to measure the rate and extent to which active pharmaceutical ingredients (APIs) are released from solid dosage forms like tablets and capsules. dissolution testers deliver precise, repeatable, and time-controlled results, making them a cornerstone of pharmaceutical quality control,  regulatory compliance, and formulation development.

The device works by immersing the dosage form in a controlled liquid medium while agitating it under standardized conditions. Over time, the amount of drug released into the solution is sampled and analyzed typically using UV-Vis or HPLC. This process simulates how a drug dissolves in the human body, providing key data on its performance and bioavailability.

Dissolution testing is essential for evaluating a wide range of solid oral products, including:

• Immediate-release and extended-release tablets

• Capsules and soft gels

• Coated and uncoated dosage forms

• Generic drug formulations (for bioequivalence)

• Research and development batches

• Stability and shelf-life studies